CTT Pilot Grant Program

 

The Center for Targeted Therapeutics (CTT)  offers a program of small pilot grants to encourage the USC and MUSC-SCCP faculty to conduct research on Targeted Therapeutics, utilizing support from at least one of the CTT core facilities.

The topics for pilot grant applications include:

        + Identification and/or validation of novel molecular targets for the treatment of a disease

        + Designing/discovering new prototype drugs (of any chemical nature) acting on a defined molecular target

        + Targeted drug delivery

        + Design and laboratory testing of novel drug combinations based on the drug target’s biology

Pilot project applications are solicited once a year. All the applications undergo peer review, and the winners are selected by the External Advisory Committee. The current round of applications has been announced (Watch the News page)

The following pilot projects were funded in the first round (2014-2015): 

Ho-Jin Koh, Ph.D.

Associate Professor, Department of Biological Sciences, USC College of Arts and Sciences.

TRB3: A Novel Mediator for Denervation-induced Muscle Atrophy

Rekha Patel, Ph.D.

Associate Professor, Department of Biological Sciences, USC College of Arts and Sciences.

PKR inhibitory peptides for treatment of type 2 diabetes and other chronic inflammatory conditions

Georgi Petkov, Ph.D.

Professor, Department of Drug Discovery and Biomedical Sciences, SC College of Pharmacy.

Identification and validation of KCNQ channels as novel molecular targets for the treatment of overactive bladder and urinary incontinence. 

The following pilot projects were funded in the second round (2015-2016):

Gabor Szalai, Ph.D.

Research Associate Professor
DBS, South Carolina College of Pharmacy

Evaluation of the Peromyscus leucopus panel for pharmacogenomics studies.

Boris Kantor, Ph.D.

Research Assistant Professor
Director of the Vector Core

Designing inducible CRISPR-CAS vector system for validation of COPZ1 gene, as a novel target for anticancer intervention.